Check out the "Hail The New World Order" poster below.
The last episode of Marvel's Agents of SHIELD saw it revealed that inside the Framework HYDRA existed instead of SHIELD. We can assume HYDRA exisits because Coulson apparently regretted becoming a SHIELD agent, so in the Framework everybody's regrets are removed, which saw Coulson become a teacher, leading to HYDRA replacing SHIELD in the alternate reality. The end of the episode did show that May did work for HYDRA as well.
Marvel's Agents of SHIELD returns with new episodes on Tuesday, April 4th at 10 pm ET/PT on ABC.